T1 - Prefrontal responses to digit span memory phases in patients with post-traumatic stress disorder (PTSD) These deactivations in PTSD patients might implicate an active inhibition of dorsolateral prefrontal neural activity during retrieval of working memory.', This deactivation was more pronounced in the right dorsolateral prefrontal cortex during the retrieval phase. The PTSD participants, but not the controls, appeared to suppress prefrontal activity during memory retrieval. In contrast, the veterans with PTSD were found to have activations during the encoding process, but followed by distinct deactivations during the retrieval process. The healthy controls showed robust hemodynamic activations during the encoding and retrieval processes. An event-related experimental design was utilized to dissociate the different phases (i.e., encoding, maintenance and retrieval) of working memory. Multichannel functional near infrared spectroscopy (fNIRS) was utilized to measure prefrontal cortex hemodynamic activations during memory of neutral (i.e., not trauma-related) forward and backward digit span tasks. In this study, the involvement of the prefrontal cortex in working memory phases was assessed among veterans with PTSD and age-/gender-matched healthy controls. However, most studies have used block designs and could not dissociate the multiple phases of working memory. These deactivations in PTSD patients might implicate an active inhibition of dorsolateral prefrontal neural activity during retrieval of working memory.Ībstract = 'Neuroimaging studies of post-traumatic stress disorder (PTSD)-related memory impairments have consistently implicated abnormal activities in the frontal and parietal lobes.

Neuroimaging studies of post-traumatic stress disorder (PTSD)-related memory impairments have consistently implicated abnormal activities in the frontal and parietal lobes.

Memory patient kf digit span